Archive for breast cancer

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Oral progestagens before menopause and risk of breast cancer

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We examined the relationship between use of progestagen-only before menopause (except for mini-pills) after the age of 40 and invasive breast cancer risk in 73 664 women from the French E3N cohort study (mean age at start of follow-up, 51.8 years; mean duration of follow-up, 9.1 years). A total of 2390 cases of invasive breast [...]

Long term effects of breastfeeding on the infant and mother

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There is increasing evidence that breastfeeding has long term beneficial effects on the infant. The most important are improved cognitive development, reduced incidence of immune related diseases (e.g. Type-1 diabetes and inflammatory bowel disease), and childhood cancers. A reduced risk of breast cancer in the mother is another important benefit.
Schack-Nielsen L, Larnkjaer A, Michaelsen KF.
Department [...]

Dietary fibre and risk of breast cancer in the UK Women’s Cohort Study

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Women who developed invasive breast cancer, 350 post-menopausally and 257 pre-menopausally, during 240 959 person-years of follow-up in the UK Women’s Cohort Study (UKWCS) were studied. This cohort has 35 792 subjects with a wide range of exposure to dietary fibre with intakes of total fibre in the lowest quintile of <20 g/day up to [...]

The potential for oxytocin (OT) to prevent breast cancer: a hypothesis

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This hypothesis proposes that carcinogens in the breast are generated by the action of superoxide free radicals released when acinal gland distension, under the influence of unopposed prolactin, causes microvessel ischaemia. Inadequate nipple care in the at-risk years leads to ductal obstruction preventing the elimination of carcinogens from the breast. The regular production of oxytocin [...]