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	<title>The Longevity Project &#187; fat loss</title>
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	<link>http://thelongevityproject.com</link>
	<description>Prevention, cognition, sustainable aging</description>
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		<title>Dairy augmentation of total and central fat loss in obese subjects</title>
		<link>http://thelongevityproject.com/dairy-augmentation-of-total-and-central-fat-loss-in-obese-subjects/</link>
		<comments>http://thelongevityproject.com/dairy-augmentation-of-total-and-central-fat-loss-in-obese-subjects/#comments</comments>
		<pubDate>Mon, 04 May 2009 13:29:24 +0000</pubDate>
		<dc:creator>TLP</dc:creator>
				<category><![CDATA[Abstracts]]></category>
		<category><![CDATA[dairy]]></category>
		<category><![CDATA[fat loss]]></category>
		<category><![CDATA[obesity]]></category>
		<category><![CDATA[yoghurt]]></category>

		<guid isPermaLink="false">http://thelongevityproject.com/?p=508</guid>
		<description><![CDATA[BACKGROUND AND OBJECTIVE: We have previously demonstrated an antiobesity effect of dietary Ca; this is largely mediated by Ca suppression of calcitriol levels, resulting in reduced adipocyte intracellular Ca2+ and, consequently, a coordinated increase in lipid utilization and decrease in lipogenesis. Notably, dairy Ca is markedly more effective than other Ca sources. DESIGN: Obese subjects [...]]]></description>
			<content:encoded><![CDATA[<p class="abstract">BACKGROUND AND OBJECTIVE: We have previously demonstrated an antiobesity effect of dietary Ca; this is largely mediated by Ca suppression of calcitriol levels, resulting in reduced adipocyte intracellular Ca2+ and, consequently, a coordinated increase in lipid utilization and decrease in lipogenesis. Notably, dairy Ca is markedly more effective than other Ca sources. DESIGN: Obese subjects were placed on balanced deficit (-500 kcal/day) diets and randomized to control (400-500 mg Ca/day; n = 16) or yogurt (1100 mg Ca/day; n = 18) treatments for 12 weeks. Dietary macronutrients and fiber were held constant at the US average. MEASUREMENTS: Body weight, body fat and fat distribution (by dual-energy X-ray absorptiometry), blood pressure and circulating lipids were measured at baseline and after 12 weeks of intervention. RESULTS: Fat loss was markedly increased on the yogurt diet (-4.43+/-0.47 vs -2.75+/-0.73 kg in yogurt and control groups; P&lt;0.005) while lean tissue loss was reduced by 31% on the yogurt diet. Trunk fat loss was augmented by 81% on the yogurt vs control diet (P&lt;0.001), and this was reflected in a markedly greater reduction in waist circumference (-3.99+/-0.48 vs -0.58+/-1.04 cm, P&lt;0.001). Further, the fraction of fat lost from the trunk was higher on the yogurt diet vs control (P&lt;0.005). CONCLUSION: Isocaloric substitution of yogurt for other foods significantly augments fat loss and reduces central adiposity during energy restriction.</p>
<p class="abstract"><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;Cmd=Search&amp;Term=%22Zemel%20MB%22%5BAuthor%5D&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus"><strong>Zemel MB</strong></a>, <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;Cmd=Search&amp;Term=%22Richards%20J%22%5BAuthor%5D&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus"><strong>Richards J</strong></a>, <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;Cmd=Search&amp;Term=%22Mathis%20S%22%5BAuthor%5D&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus"><strong>Mathis S</strong></a>, <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;Cmd=Search&amp;Term=%22Milstead%20A%22%5BAuthor%5D&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus"><strong>Milstead A</strong></a>, <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;Cmd=Search&amp;Term=%22Gebhardt%20L%22%5BAuthor%5D&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus"><strong>Gebhardt L</strong></a>, <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&amp;Cmd=Search&amp;Term=%22Silva%20E%22%5BAuthor%5D&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus"><strong>Silva E</strong></a>.</p>
<p class="affiliation">Department of Nutrition, The University of Tennessee, Knoxville, TN 37996-1920, USA. mzemel@utk.edu</p>
<p class="abstract"><span class="ti"><strong> </strong><span title="International journal of obesity (2005)."><a href="javascript:AL_get(this,%20'jour',%20'Int%20J%20Obes%20(Lond).');">Int J Obes (Lond).</a></span> 2005 Apr;29(4):391-7.</span><span class="featured_linkouts"><a href="http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?PrId=3094&amp;itool=AbstractPlus-def&amp;uid=15672113&amp;db=pubmed&amp;url=http://dx.doi.org/10.1038/sj.ijo.0802880" target="_blank"><img id="linkout-icon-def-lo_npg" src="http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.nature.com-images-lo_npg.gif" border="0" alt="Click here to read" /></a> </span><span class="linkbar"><script>&lt;!-- 
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